Sufferers 2DM are at increased risk of developing dementia and Alzheimer’s disease and have been reported to have lower cognitive performance compared to age-matched healthy controls. Several studies have linked it to brain atrophy.

The relationship between typical brain aging and that seen in type 2 diabetes and found a pattern of neurodegeneration similar to that of aging, but progressing more rapidly.

The results suggest that by the time diagnosis occurs, there may already be significant structural damage to the brain.

The structure and activity of the brain was also compared, discovering a decrease in gray matter, which is even more pronounced in those with 2DM. This is 6.2% in the ventral striatum and also in other regions.

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